first_imgDerby boss Lampard gives up on Chelsea defender Ampaduby Freddie Taylor10 months agoSend to a friendShare the loveDerby County have been rebuffed in their attempts to sign Chelsea defender Ethan Ampadu on loan, confirmed Rams boss Frank Lampard.The 18-year-old can play at centre-back and centre-midfield and Lampard believes it is this versatility that makes him a prized asset at Stamford Bridge.”We have asked, but I don’t think he’s leaving Chelsea,” he told reporters. “He can play in a few positions, that’s why he would be so valuable to anybody and why he’s staying at Chelsea.”People thought we did a lot of business in the summer, but our actual net spend was very negligible.”I had to bring in personnel to try to change the style and that’s not a one-window solution, that’s probably two or three-window. This window will be quiet for us.” TagsTransfersAbout the authorFreddie TaylorShare the loveHave your saylast_img read more

first_imgAbout the authorPaul VegasShare the loveHave your say Chelsea boss Lampard delivers new Kante updateby Paul Vegasa month agoSend to a friendShare the loveChelsea boss Frank Lampard says N’Golo Kante could be back for their Champions League tie with Lille.Kante missed victory over Brighton yesterday with a hamstring strain.Lampard said, “I spoke to N’Golo about it and I didn’t want to take the risk. “He’s so important for us but it’s been difficult for him to get going because of the break-up of his pre-season, with his injury carried over from last season. It wasn’t right to risk it today but he could have a chance for Lille.” last_img read more

first_imgAbout the authorFreddie TaylorShare the loveHave your say Ex-Man Utd striker Van Persie: Pogba played out of positionby Freddie Taylor24 days agoSend to a friendShare the loveFormer Manchester United striker Robin van Persie thinks Paul Pogba should be playing further in Ole Gunnar Solskjaer’s side.The World Cup winner has lined up primarily as a defensive midfielder under the Norwegian this season.Speaking after Monday’s draw with Arsenal, van Persie said: “For him, the coach, for us, for everyone, it’s just important to choose a position.”I would play him not as a defensive midfielder, and not as a number 10 but in between – [the] number eight position. “So, he still has his freedom, he’s not judged then on 20-plus goals a season, if he scores 10-plus goals, makes assists, everyone will look differently at him then, but it needs to be clear for everyone.” last_img read more

The first season of college football’s playoff era will come to a close Monday night, as the Oregon Ducks face the Ohio State Buckeyes for the national championship.The Ducks come into the contest favored by most sources, including the consensus of sportsbooks in Las Vegas and ESPN’s Football Power Index (FPI). But there’s disagreement on the degree of Oregon’s edge. The FPI, which includes results from every game of the 2014 season (plus a preseason rating as a prior), thinks Oregon would beat Ohio State by about five points at AT&T Stadium or another neutral field. Vegas, however, spent most of the past week favoring the Ducks by more — as many as 6.5 to seven points, according to the bookmakers listed at VegasInsider.com.This was looking like a sure sign of the markets’ skepticism over the ability of Buckeyes quarterback Cardale Jones. Jones began the 2014 season third on Ohio State’s QB depth chart, behind Heisman candidate Braxton Miller and touted redshirt freshman backup J.T. Barrett. Then Miller was injured and lost for the season in an August practice, upon which Barrett took the reins and led the Buckeyes to a 11-1 record (on the strength of one of the nation’s best passing performances) before going down with a season-ending injury in late November.Now Jones is at the helm.Jones, a sophomore, was only regarded as the 41st-best QB prospect in his freshman class, according to Phil Steele’s recruiting aggregations, and had thrown just 19 career passes before starting in the Big Ten title game against Wisconsin. But Jones and the Buckeyes were spectacular in that game, winning 59-0, and then upset favored Alabama in the College Football Playoff semifinals. (Jones’s numbers were less impressive against Alabama than against Wisconsin — but then again, Alabama also has a slightly tougher pass defense.)It effectively created an interesting Bayesian problem: How do we balance a sample of two great games against the prior assumption that Jones is a lightly regarded third-stringer? The initial discrepancy between Vegas’s Oregon-Ohio State point spread and that generated by season-long power ratings seemed to indicate how much of a downgrade Jones was relative to Barrett: roughly 1.5 to two points by the market consensus. As a point of comparison, this is a smaller margin than the typical gap between a starter and a backup QB in the NFL.Complicating matters now, though, was the news early Saturday that Oregon wide receiver Darren Carrington, the team’s second-leading receiver, failed a drug test and was declared ineligible for the title game. That shrunk Vegas’s consensus edge for Oregon down to about 5.5 points by Saturday morning — nearly the same as the FPI predicts using both teams’ full-season numbers. (The game’s line has since returned to a consensus of 6.5 points favoring Oregon, as of Monday morning.)Even so, it will be worth keeping an eye on which effect is bigger, and whether the market’s implicitly Bayesian assessment of Jones turns out to be on the money or not. It’s no stretch to say the accuracy of that appraisal could determine Ohio State’s fate Monday night. read more

first_imgThere are over 44 million donkeys worldwide and many are suffering unimaginable abuse and neglect in the hands of their owners.Unfortunately, a worryingly increasing number of such incidents has reportedly been linked to one of Greece’s most beautiful islands, Santorini.Islanders have been using donkeys and mules as taxis for decades if not longer, as the caldera perched town of Thira is not easily approachable from the port.Even though there is a double direction asphalted road for buses and cars, it is often congested with traffic whereas the picturesque ride on the cobblestone alternative is more popular amongst visitors.With the unprecedented increase in tourist arrivals on the island over the past two years, so have increased cases of animal neglect and abuse. Voted the world’s number one popular island destination for 2017, Santorini’s success surpasses the municipal authorities’ ability to manage the tourist intake during peak periods.Even though the port of Santorini put a limit on the visitors allowed on the island each day, that number is still too high to manage, especially when it comes to transportation.Photo: Caters News.For this year the Cycladic destination culled the number of cruise ships that can land and disembark passengers limiting visitors to 8,000 per day, down from over 12,000 in 2017 and 70,000 people in 2016.Those day trips to the island have been the residents’ main source of income, with most cruise ships coming from the U.S., the U.K. and Russia.Constant flow of people sees donkey ride demand sky-rocketChristina Kaloudi, the founder of the Santorini Animal Welfare Association, said: “Donkeys are pretty much in work [all] year round. They are made to work in terrible conditions without adequate water, shelter or rest, and then I find them tied outside my shelter, barely alive.”According to Kaloudi, during the summertime and especially in peak season, donkeys might make four or five journeys going up more than 500 steps from where the boats land, bringing tourists onto the island, to the main town of Fira.“Over the years, as the weight of tourists has risen, the number of donkeys getting hurt has risen too,” Kaloudi said.Photo: Caters NewsMeanwhile, a spokesperson for the charity Help the Santorini Donkeys complained to several media outlets that “obese and overweight tourists combined with the lack of shade and water, heat and cobbled steps is what’s causing such a problem.“There should be a weight restriction. With donkeys it should be no more than eight stone, but how would that be imposed? It’s recommended animals carry no more than 20 percent of their body weight.”As a result, some opportunists who jumped into the donkey and mule breeding industry as a means to increase their profit have now resort to using cross-bred mules,” as the donkeys just aren’t strong enough”.Mules have the capacity to bear a larger weight, however, campaigners insist that the weight they are being asked to carry up steep hills under the scorching sun is “torture”.Last week a shocking video showing men that profit from donkey rides attack a peaceful protest by animal welfare activists went viral.In the video posted last Friday, the men verbally harass and seriously injure three women.Konstantina Lyrou, a witness that recorded the incident said that one of the activists was a 15-year-old girl. The men are documented throwing the women’s belongings off the cliff, punching one and dragging another until her shoulder is dislocated. International animal welfare organisation The Donkey Sanctuary has also visited the picturesque island documenting several cases of mistreated donkeys and mules due to lack of food and water, lack of rest, abuse, and injuries due to the weight and the ill-fitting saddles.The organisation sent out a team of members to investigate the animals’ well-being and prepare a report while they also plan to demand that the Greek government takes action to ensure better conditions for the poor critters.“Everything increases, including the volume of trash and water consumption,” Santorini Mayor Nikos Zorzos confirmed. “Over-exploitation will lead to environmental impoverishment, and the waste of natural resources will sap the island’s attraction.“No more hotels, no more cars,” added Zorzos, who has appealed to the government to take measures to curb development on the island.Watch a video documenting the conditions below: Facebook Twitter: @NeosKosmos Instagramcenter_img Αυτό είναι το Κρατος και η Παιδεία τους..Αισχος και ντροπή…#santorinidonkeys #humanabuse #animalabuse #donkeysPosted by Konstantina Lyrou on Friday, July 27, 2018last_img read more

first_imgArsenal forward Danny Welbeck will reportedly join teammate Aaron Ramsey in leaving the club as a free agent in the summerThe England international’s existing contract with Arsenal will expire at the end of the season, much like Ramsey’s own predicament.Welbeck has been on a good run of form lately and expressed his hope that manager Unai Emery will hand him more opportunities to play.Roberto Firmino, LiverpoolVirgil van Dijk praises Roberto Firmino after Liverpool’s win Andrew Smyth – September 14, 2019 Virgil van Dijk hailed team-mate Roberto Firmino after coming off the bench to inspire Liverpool to a 3-1 comeback win against Newcastle United.But now the Daily Mirror claims that talks between Welbeck’s representatives and Arsenal are nowhere near close to completion and now he seems set to leave the Emirates Stadium next summer.The 27-year-old will be free to sign with a foreign club in January and previously attracted the interest of Turkish giants Galatasaray in August.Welbeck has scored four goals in seven appearances for Arsenal this season, but is yet to start a single game in the Premier League.last_img read more

first_imgValencia boss Marcelino believes Rodrigo Moreno and Michy Batshuayi will end their goal droughts despite his side’s 1-0 narrow win at Getafe.Dani Parejo’s VAR penalty saved the blushes of Rodrigo who had not scored since the opening day of the season, while Batshuayi was absent from the squad, leaving the Chelsea loanee on just two goals for the campaign.“Winning always matters,” Marcelino told Football Espana after Valencia won back-to-back games for the first time in 2018-19.“I saw a very good Valencia in the first half, but we had to be comfortably ahead at half-time.“When you’re forgiving, you usually pay and Getafe threatened to make us do that early in the second half.“However, the VAR helped us. It went against us last week and ultimately we won because of it. It imparted justice.Ernesto Valverde, Lionel Messi, BarcelonaValverde downplays fears over Lionel Messi’s Barcelona future Andrew Smyth – September 13, 2019 Ernesto Valverde believes Lionel Messi’s comments on his Barcelona future have been taken out of context, and gave an update on the forward’s injury.“Rodrigo’s drought is football. It’s a situation that, no matter how much you think about it, has no explanation.“The important thing is that he’s a very good player. We need Rodrigo at his best. He had a great game against Young Boys the other night.“What he missed here were three clear goals, but he’ll eventually score with his back.“His work in the last third is good, he’s just lacking that edge to his finishing. He’ll be back scoring after the international break.“I’m not unhappy with Batshuayi. I’m always positive, I try to help and transmit things to the players, but I also demand things at the same time.“It’s tough. I always try to be fair and in this situation, I have to make decisions. The hardest thing for a Coach is to pick a matchday squad of 18 players and 11 to start after that because it’s discriminating.”last_img read more

first_imgAP Memorial candles outside the Swedish Embassy in Helsinki on Friday evening April 7, 2017. The driver of a hijacked beer truck is wanted by police after the truck crashed into an upscale department store in central Stockholm on Friday, leaving dead and injured in its wake. (MARKKU ULANDER / Lehtikuva via AP)A hijacked beer truck plowed into pedestrians at a central Stockholm department store Friday, killing four people, injuring 15 and sending screaming shoppers scattering in panic in what Sweden’s prime minister called a terrorist attack.A nationwide manhunt was launched and one person was arrested following the latest use of a vehicle as a weapon in Europe.Nearby buildings were locked down for hours in the heart of the capital and the main train station was evacuated.“Sweden has been attacked,” Prime Minister Stefan Lofven said in a nationally televised press conference. “This indicates that it is an act of terror.”He added: “The country is in a state of shock.”The truck traveled for more than 500 yards (meters) along a promenade known as the Drottninggatan and smashed into a crowd outside the Ahlens department store about 3 p.m. It came to rest in the entrance to the building. TV footage showed smoke coming out of the store after the crash.“People were screaming and running in all directions,” said Brandon Sekitto, who was in his car nearby.He added that the truck “drove straight into the Ahlens entrance.”“I saw the driver, a man in black who was light around the face area,” Brandon told Swedish daily Dagens Nyheter. “I heard how some women were screaming, ‘Run, run!’”Although there was confusion throughout the day on the number of victims, the Stockholm City Council said in the evening that four had been killed and 15 were wounded, nine seriously.Authorities evacuated the nearby Central Station, a hub for regional trains and the subway system. All trains to and from the main station were halted and several large shopping malls in Stockholm were shut down. Sweden’s national theater, Dramaten, canceled three performances Friday evening.Sweden’s prime minister calls Stockholm attack a “terrible act of terror” https://t.co/NlcyoTYBMl pic.twitter.com/sMxAW4yXBG— Bloomberg (@business) April 7, 2017Police arrested a man in Marsta, a northern Stockholm suburb close to the international airport.“We have arrested one in whom we are particularly interested,” Jan Evensson of the Stockholm police told a news conference.He said the person looked like the man depicted wearing a greenish hood in a surveillance camera photo the police released earlier.“We continue to investigate at full force,” Evensson said, urging people not to go to central Stockholm.Stefan Hector of Sweden’s national police said the working hypothesis was that “this is an act of terror.”The Swedish brewery Spendrups said one of its trucks had been hijacked a few blocks from the scene earlier in the day.“It is one of our delivery trucks. In connection with a delivery to a restaurant called Caliente, someone jumped into the truck and drove it away while the driver was unloading his delivery,” Spendrups spokesman Marten Luth told the Swedish news agency TT.The beer company’s truck driver was not injured, he said.The truck crash appeared to be the latest attack in Europe using a vehicle.In an attack last month claimed by the Islamic State group, a man drove into a crowd on London’s Westminster Bridge, killing three people and injuring many others before stabbing a policeman to death. He was shot and killed by police. A fourth person, a woman thrown into the Thames by the force of the car attack, died Thursday.The IS group also claimed responsibility for a truck attack that killed 86 people in Nice, France, in July 2016 during a Bastille Day festival, as well as another truck attack that killed 12 people at a Christmas market in Berlin.Swedish King Carl XVI Gustaf cut short a visit to Brazil on Friday to return home and sent the royal family’s condolences to the families of the victims.Condolences poured into Sweden. In neighboring Finland, President Sauli Niinisto said he was shocked by the “maniac act of terror,” adding “every terror attack is to be equally condemned. But it touches us deeply when such an attack takes place in our Nordic neighborhood.”Danish Prime Minister Lars Loekke Rasmussen called the attack a cowardly attempt “to subdue us and the peaceful way we live in Scandinavia.”Paris Mayor Anne Hidalgo said the Eiffel Tower’s lights will be turned off from midnight Friday in homage. She expressed her “strong emotion” over “this new terrorist attack of immense cowardice.”EU Council President Donald Tusk said in a tweet that “my heart is in Stockholm this afternoon. My thoughts are with the victims and their families and friends of today’s terrible attack.”European Commission President Jean-Claude Juncker said “one of Europe’s most vibrant and colorful cities appears to have been struck by those wishing it — and our very way of life — harm.”Juncker also said “an attack on any of our (EU) member states is an attack on us all” and that Sweden can count on EU help.In February, U.S. President Donald Trump suggested that Sweden could be the next European country to suffer the kind of extremist attacks that have devastated France, Belgium and Germany. Two days after his remarks, a riot broke out in predominantly immigrant suburb of Stockholm where police opened fire on rioters, a surprise to many Swedes who aren’t used to officers using guns.Friday’s crash was near the site of a December 2010 attack in Stockholm in which Taimour Abdulwahab, a Swedish citizen who lived in Britain, detonated a suicide bomb, killing himself and injuring two others.Abdulwahab had rigged a car with explosives in the hope the blast would drive people to Drottninggatan — the street hit Friday — where he would set off devices strapped to his chest and back. The car bomb never went off, and Abdulwahab died when one of his devices exploded among panicked Christmas shoppers. Sharelast_img read more

first_imgA teen charged with robbing another teen as he walked to pick up his cap and gown from Frederick Douglas high school in June, has been charged with the shooting of a 42 year-old Owings Mills man in July.Kyree Trimon Greene was charged with shooting a 42-year-old man in Maryland. (Photo/Baltimore City Police Department)Kyree Trimon Greene of the 2600 block of Francis Street in Baltimore’s Penn North, is charged with attempted first-degree murder and other charges for shooting the 42 year-old man in Baltimore County on July 17th.Greene who just turned 19, was charged prior in the botched robbery of a 17 year-old student going to pick up his cap and gown. The student told police someone stuck a gun to his back and tried to rob him. In the process, a struggle ensued and Greene accidently shot himself with the victim gaining control of the gun. Greene fled on foot and Baltimore Police did not know at that time if Greene was a student.  Using video surveillance, police later identified Greene as the suspect in that robbery.A quick search of the Maryland Case Search shows various charges for Greene in the Frederick Douglas robbery including Fire arm use, First and Second degree assault, reckless endangerment, and discharging a firearm.Greene is also charged in the shooting of another teen. A 16 year-old that was walking home with friends in Howard Park in May when a masked man opened fire hitting the teen in the thigh. Police later identified Greene as the shooter.According to Maryland Case Search, Greene has been charged with Attempted First and Second degree murder, First and Second Degree assault, Firearm on a minor and reckless endangerment as well as discharging a firearm.In the Owings Mills shooting that happened in July, police were called to Reisterstown Road and Pleasant Ridge Drive for a person shot multiple times. Police found a 42-year-old man.  The victim got out of his car to confront Greene when Greene made a U-turn in front of him, cutting him off. Greene then fired several shots at the victim.Greene was arrested in Baltimore, five days later according to case search. Officers near Druid Hill Park noticed Greene was armed and a chase ensued before he was caught.Greene is being held without bail in Baltimore.last_img read more

first_imgAuthorities say multiple people have been shot in northeast Maryland in what the FBI is describing as an “active shooter situation.” (Jerry Jackson /The Baltimore Sun via AP)Worker Walter Zambrano, 64, said he was fortunate that he was in a bathroom when shooting broke out during a 9 a.m. morning break when workers were gathering in a cafeteria. He hid in the bathroom until the shooting stopped, fearing for his life.The person was “shooting like crazy, bam! bam! bam!” Zambrano said, speaking in Spanish. “Everyone was screaming, running this way and that. I didn’t know which way to run.”Harford County Sheriff Jeffrey Gahler told a news conference hours later that the woman had been identified as a temporary employee, Snochia Moseley of Baltimore County. It appears only one weapon was used — a 9 mm Glock handgun that was registered in Moseley’s name — and no shots were fired by responding law enforcement officers, he added.“She had reported for her workday as usual, and around 9 a.m. the shooting began, striking victims both outside the business and inside the facility,” Gahler said.He called it a “senseless crime,” adding investigators didn’t have any motive immediately after the shooting.Three people were fatally shot and three more were wounded but expected to survive, the sheriff said. The victims were not immediately identified. Moseley died at a hospital from a self-inflicted gunshot wound, according to the sheriff.The sheriff said the call about shots fired came in at about 9:06 a.m. Thursday and deputies and other officers were on the scene in just over five minutes. The shooting began outside the business and continued inside, he said.Krystal Watson said her husband Eric works at the facility and told her told her the suspect had been arguing with somebody else near a time clock after a “town hall meeting.”“And she went off,” she said.“She didn’t have a particular target. She was just shooting,” Watson said as she left a fire station where relatives sought to be reunited with loved ones.Susan Henderson, spokeswoman for the drugstore chain Rite Aid, described the building where the shooting took place as a support facility adjacent to a larger building. The company said in a statement that the facility had been closed temporarily and grief counselors were being made available to workers.The company didn’t immediately respond to an inquiry about Moseley’s employment history.Mike Carre, an employee of a furniture logistics operation next to the distribution center, said he helped tend to a wounded man who came hobbling in, bleeding from his leg. He called 911 before helping colleagues wrap the man’s blood-soaked jeans above his injury to cut off blood flow.Carre said the man told him the shooter “just came in in a bad mood this morning. He said she’s usually nice. But today, I guess it wasn’t her day. She just came in to pick a fight with someone.”“She pulled out a gun and she just started shooting at her co-workers.”The attack came nearly three months after a man with a shotgun attacked a newspaper office in Annapolis, Maryland, killing five staff members. Authorities accused Jarrod W. Ramos of attacking The Capital Gazette because of a longstanding grudge against the paper. It came less than a year after a fatal workplace shooting less than 10 miles (16 kilometers) from the warehouse, in which five were shot, three fatally.Harford County Executive Barry Glassman said that, unfortunately, shooting like this are “becoming a too-often occurrence” in the nation.On Thursday, 33-year-old Dominique Norton of Aberdeen, endured an excruciating wait of nearly two hours to be reunited with her mother, 62-year-old warehouse worker Irene Norton. The younger woman said she didn’t know that her mother was unharmed until she got off a bus at the fire station and they tearfully embraced.“I busted out crying. I was relieved and shaken,” she said. “I am praying for all of the victims.” Updated Sept. 21By The Associated PressWorkers say they endured horrifying moments of wild gunfire and terror as a woman working a temporary job at a drugstore warehouse in Maryland fired on colleagues with a handgun, killing three people before fatally shooting herself.The shooting, which authorities said was touched off when the worker got into an argument Thursday morning, sent survivors screaming and running in all directions from the Rite Aid distribution center in northeastern Maryland. Others nearby helped the wounded and one person tied blood-soaked jeans around an injured man’s leg trying to staunch the bleeding.last_img read more

first_img This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Journal information: Cell Reports Explore further (Phys.org)—Every organ strikes its own balance between self-renewal and differentiation. At one extreme is the brain, where only a few isolated outposts are known to contribute to a largely quiescent population. At another extreme are the testes, where at least in males, prolific germline turnover is maintained amidst a protracted and deliberate multi-month creation cycle. Perhaps surprisingly, both organs are uniquely immunoprivileged against various vascular indiscretions and yet rely on various myeloid-derived cells like macrophages or microglia to instruct important structural maturations. The so-called stem cell ‘niche’ is the microenvironment of the stem cell: all those physical and molecular intangibles that nourish, shield and inform its major life decisions. In creatures like worms and flies a well-defined stem cell niche is distally localized within a polarized gonad. By contrast, each testes of the mammal can contain up to 40,000 potential stem cell niches more-or-less randomly dispersed among its seminiferous tubules. A recent paper published in Cell Reports has removed some of the mystery in the mammalian reproductive system by showing that a unique class of testicular macrophages define its putative stem cell niche.Perhaps even more importantly, they also show that these macrophages control spermatogonial differentiation through the expression of critical factors including CSF1 (colony-stimulating factor) and retinoic acid synthesis enzymes. When the researchers ablated the macrophages by making them selectively and transiently susceptible to the diphtheria toxin, they found a drastic reduction in the number of spermatogonia. This new found responsibility of macrophages complements their previous known testicular functions in promoting steroidogenesis in Leydig cells. They are also known to be intimately involved in vascular development in several places, including the brain. We should mention that the immune barrier in the brain is due mainly to the endfeet of astroglial cells while in the testes it is created by tight junctions in the Sertoli cells that nurse the developing spermatogonia.The single spermatogonium is the most undifferentiated cell within the prevailing model of the spermatogonial stem cell hierarchy. In the fullness of time each one progresses through an incomplete cytokinesis, giving rise to syncytial cysts of spermatogonia progeny that are held together in formation by cytoplasmic bridges. In this way those cells in the syncytium that lack and X chromosome can still get copies for things like glucose 6 phosphate dehydrogenase. Similarly those cells that find themselves without a Y still have access to essentials like the RBM gene, which is critical later in spermatogenesis. Testes. Credit: smithlhhsb122.wikispaces.com More information: The New Director of “the Spermatogonial Niche”: Introducing the Peritubular Macrophage, Cell Reports, Volume 12, Issue 7, p1069–1070, 18 August 2015. dx.doi.org/10.1016/j.celrep.2015.07.057Macrophages Contribute to the Spermatogonial Niche in the Adult Testis, Cell Reports, Volume 12, Issue 7, p1107–1119, 18 August 2015. dx.doi.org/10.1016/j.celrep.2015.07.015 Mechanisms for continually producing sperm © 2015 Phys.org For most men, the only time they ever hear the word macrophage in reference to their testicles is when it comes time for the vasectomy. Upon being told during that actual sperm production is totally unaffected by a vasectomy, any reasonable man might be expected to wonder, perhaps aloud, ‘what happens to all the sperm’? Typically there is some mumbling about macrophages taking care of all that, although the actual details are a bit shoddy. This new evidence regarding the intimate relationship between macrophages, spermatogenesis, and perhaps even spermicide, points to the indebtedness we have to these dynamic cells.Since we have already broached the subject we might take the opportunity to share a few more illuminative details that may benefit anyone undergoing significant alterations to their reproductive plumbing. While a general attitude of ‘the less you know, the better’ may often prevail in such matters, there are some things a patient should probably know. In up to half of patients something known in the business simply as ‘epididymal blowout’ will occur. This is something every bit as horrid to imagine as it sounds. Typically, pressure in the vas deferens (which usually is tied off or electrocauterized) builds up over the course of several weeks post-op to the point that it ruptures, frequently accompanied by some pain and possible formation of epidydimal cysts. Fortunately, through a cooperative macrophage effort, this situation largely resolves on its own.However for some men something even more sinister lurks within. Another word that can bring even the strongest to their knees is ‘re-canalization’. This situation is also precisely as it sounds—complete regrowth and functional connection of a severed vas deferens. It is not yet known exactly how or when this can occur other than to say that ‘where there’s a will there’s a way’. For men lucky enough to avoid any of these potential pitfalls there is probably only one remaining concern: what happens to levels of testosterone?Studies have apparently shown that testosterone levels remain the same on average. What such a devilish statement hides is that depending on your particular constitution and sequalae, you might your own individual expect levels to change, either for the better or for worse. In other words, with evidence in literature for both increases and decreases, it is fair to say we need more research on how such things are ultimately controlled in the gonads. Citation: Macrophages create the elusive spermatogonial stem cell niche (2015, September 3) retrieved 18 August 2019 from https://phys.org/news/2015-09-macrophages-elusive-spermatogonial-stem-cell.htmllast_img read more

first_imgHoly cow!!! Delhi this weekend made this expression towards a philanthropic cause (which was saving our Indian desi cow). How? By organising an exhibition plus fest centered on a conscious awakening towards going back to nature and preserving nature for our own happy and healthy future.Organised at Select City Walk, Saket, the Ahimsa Bazar or Holy Cow Music Fest, was organised by Holy Cow Foundation.  It had stalls opened from 11 am till 10 pm aimed at promoting products made from cowdung (manure, dhoopbati, agnihotra samidha, air purifier kit etc) and urine (ark, pesticide, phenyel etc.); the foundation is working towards enabling sustainability of the cow and creating awareness about apathetic condition of our domestic animals. Also Read – ‘Playing Jojo was emotionally exhausting’Visitors could select from a sumptuous menu consisting of vegetarian and vegan food and vegan ice-cream. Also, there was choice of organic vegetables and products as well as ayurveda and Holy Cow panchgavya health products. For the nature conscious, there were stalls on home composting units and organic compost and for those with literary interest, there were books on display by Indological book store. The festival also had some entertainment value to it with scintillating performances by the snake charmers sans the live snakes and kajri sangeet. For the classically attuned, there were breathtaking jugalbandi on table and the lion dance of the north east. Also Read – Leslie doing new comedy special with NetflixThe music extravaganza continued till late in the evening with rock Kirtan by Vraj Vadhu group of ISKON, including street plays and several other performances.Covered with glee and fun, the event had an underlying message which highlighted the following points- Stop cow slaughter. Stop any kind of animal slaughter for food and pleasure and respect all forms of life and live with nature. Encourage farmers to produce organic products by creating a demand for them and use cow milk, curd and ghee in your homes since these are ambrosia for humans amongst others The major concern marked was indiscriminate slaughter of cows to export meat (in our country everyday 50,000 cows are being slaughtered) and excessive use of chemical fertilizers in agriculture (today Punjab is known as the cancer  capital of India) have become the major cause of growing instance of women becoming barren and men becoming impotent, rising graphs of diseases, mental stress and disorders, disorientation of youth and growing aggression in our society.This is the second time the festival is being held and the response was quite heartening.last_img read more