The investor calls for actively managed, long-only products; enhanced index or extended products will not be considered.Further, all type of traditional investment styles will be accepted, while minimum volatility and other single-risk-premia strategies will not.For products with active, fundamental, bottom-up approaches, quantitative approaches – “regardless of base in fundamental stock ratios” – will be prohibited, as will be the use of derivatives or leverage.The expected excess return level is 2-4% per annum, with a “suitable” tracking error.Products with a three-year track record “are a must”.The closing date for applications, stating performance to the end of June, is 15 October.If you do have any questions regarding this search, please email email@example.com. Questions will not be accepted after 13 October. An undisclosed pension fund based in the Nordic region has tendered a $350m (€219m) US large-cap equity mandate using IPE-Quest.According to search QN1458, asset managers must show they have, historically, “been capable of beating the MSCI USA or similar benchmarks”, independently of the market or own investment style. The manager must also be able to offer the strategy in a segregated mandate, and willing to comply with the pension fund’s SRI policy.The initial size of the mandate is expected to be $350m but with a “potential for twice the amount for the right manager”.
Warning Graphic Subject MatterParents Opposed to Pot is bringing awareness to the link between marijuana and violence in America, but we want the public to know that our hearts break for all the victims and their families and friends. Many of us are victims too. This was a difficult video to produce but the public needs to know marijuana is a risk factor for violence, especially today’s high potency marijuana.Resources for Think Ya Know? Is Marijuana a Risk Factor for Violence?Metanalysis- “Cannabis use in this population is a risk factor for violence.”https://ajp.psychiatryonline.org/doi/…Tell Your Children the Truth About Marijuana, Mental Illness, and Violencehttps://www.simonandschuster.com/book…Cases of cannabis-induced psychosis increase during COVID-19 pandemichttps://www.daily-chronicle.com/2020/…Arizona child deaths marijuanahttps://www.azdhs.gov/documents/preve…Florida child deathshttps://cdn.ymaws.com/www.fadaa.org/r…Texas child deathshttps://www.dfps.state.tx.us/About_DF…Lewisville Texas, father kills 16-month old sonhttps://www.foxnews.com/us/texas-dad-…https://cbsaustin.com/news/local/nort…1st day of marijuana legalization 2 shot in home invasion to steal marijuana. 9-year-old homehttps://komonews.com/news/local/polic…Richard Kirk kills wife after consuming marijuana candyhttps://www.rmpbs.org/blogs/news/excl…A 15-year-old boy died and a 14-year-old is possibly paralyzed after apparently trying to steal marijuana plants from a Denver backyard.https://www.9news.com/article/news/cr…Deputy Parishhttps://castlerocknewspress.net/stori…Fountain Colorado 2 teens shot marijuana drug deal, brought 1 year to drug dealhttps://www.kktv.com/content/news/2-t…Columbine shootinghttps://www.theguardian.com/us-news/2…https://www.denverpost.com/1999/04/21…Tucson shooterhttps://www.laweekly.com/marijuana-tu…Colorado Theater Shooterhttps://www.laweekly.com/james-holmes…Dylan Roof church shooterhttps://www.nytimes.com/2015/07/17/us…Colorado Springs Halloween shooterhttps://www.csindy.com/IndyBlog/archi…Colorado Planned Parenthood shooterhttps://gazette.com/crime/robert-dear…Kevin Janson Neal, Californiahttps://www.cbsnews.com/news/californ…https://nypost.com/2017/11/15/califor…Sutherland Springs church shooterhttps://www.nbcnews.com/storyline/tex…Parkland school shooterhttps://www.nbcnews.com/news/us-news/…
SOME of Australia’s best cricketers face a choice between heading abroad for the lucrative Indian Premier League (IPL) or staying home for domestic cricket, with the IPL expected to get the green light this week.The Emirates Cricket Board has confirmed it has received a ‘letter of intent’ from the Board of Control in Cricket in India (BCCI) to stage the tournament in Dubai, Abu Dhabi and Sharjah between September 19 and November 8.The Indian government is expected to rubber-stamp the schedule this week, meaning the 17 Australians who hold IPL contracts now face a decision as to whether they seek No Objection Certificates (NOCs) from Cricket Australia (CA) or opt to stay and represent their state sides.Under ICC regulations, players require a NOC from their home board before they are able to take part in a domestic competition staged overseas.An NOC can be issued for all or part of the tournament, and there is precedent for players leaving the tournament early for international duty, as Steve Smith and David Warner did before linking up with Australia’s World Cup training camp last year.Typically the IPL is held during Australian cricketers’ annual leave period in April and May, meaning receiving NOCs is largely a formality.But the coronavirus pandemic saw this year’s IPL – the 13th season the competition has run – delayed.Now, a clash with Australia’s domestic season looms.CA is yet to release fixtures for the domestic summer, with the Marsh One-Day Cup and Marsh Sheffield Shield competitions typically starting in September and October respectively.How those competitions proceed in light of the health and border restrictions associated with the ongoing pandemic remains to be seen.The timing of the IPL season is also serendipitous for Australia’s internationals, with a six-match limited overs series in the UK reportedly to wind up by September 16. It is expected that three T20s will be followed by three ODIs.Under the latest health measures in the UAE, visitors who arrive with a certificate proving a negative COVID-19 test within the past 72 hours do not need to quarantine, with England and Australian players expected to share a chartered flight to the UAE from the UK.The 26-man preliminary squad Australia has named includes IPL top-earner Pat Cummins, who was bought by Kolkata for A$3.16M at the auction last December, and joins Steve Smith, David Warner and Glenn Maxwell as Australians on $1M+ deals.The 17 Australians involved in the IPL hold contracts that were worth a collective A$17.145 million at the time of the auction last December, but are now worth a touch over A$16M due to currency fluctuations.The confirmation of the IPL schedule could also cause repercussions for Australia’s international schedule, with T20 International series against West Indies and India currently scheduled for October, while players returning from the IPL are set to face a 14-day quarantine period on their return home – assuming current travel protocols remain in place.The KFC BBL is currently set to open on the same December 3 date as the scheduled start for Australia’s Test series with India in Brisbane, and international players featuring in the Big Bash will also need to quarantine, setting up the potential for a mass arrival of leading cricket talent in Australia after the IPL.Before that, however, Australia has a Test match against Afghanistan scheduled to begin on November 21 in Perth“At the moment, we’re scheduled to play Afghanistan in Perth and we’ll be doing everything we can to get those opening bowlers to the top of their run and get cricket back being played,” Cricket Australia’s interim Chief Executive Officer Nick Hockley said last week.“As we work through the different scenario planning and as we do real-time monitoring of the health situation and the restrictions, that will inform our planning.“If there’s a change to the current schedule, then we’ll be making announcements in due course.“Currently we’re planning to go ahead, but there’s a lot to work through and a lot that can happen between now and then.”Hockley said CA was mindful of ensuring any cricketers, Australian or international, would have access to “optimal” training facilities while observing quarantine requirements, and had been learning from the ECB’s set-up where matches have been played at Southampton’s Ageas Bowl and Manchester’s Old Trafford – both venues with hotels attached.“It’s unlikely that international travel restrictions will have lifted by time India are due to come into the country, so clearly there will be testing regimes,” he said.“The reality is we will be able to test people before they get on the plane and then it’s a situation of making sure we’ve got the quarantine arrangements in line with government and health authority protocols.“What we’re working on is making sure that, even within that quarantine environment, players have got the absolute best training facilities so their preparation for the matches is as optimal as it can possibly be.“Whether it’s a hotel on site, or whether there are hotels in close proximity to venues, creating that environment where we’re minimising the risk of infections and creating a bio-secure environment is the absolute priority.“There’s a huge amount at stake if we’re unable to do that.“Adelaide Oval has got a hotel (due for completion in September), and we’re obviously in discussion with all venues, but that does provide a facility not dissimilar to Old Trafford (in Manchester) or the Ageas Bowl (Southampton) where a hotel is integrated into the venue.”India has become a global hotspot for the coronavirus pandemic, and the IPL has been forced to be held outside of the country.The IPL was partially held in the UAE in 2014, while the entire 2009 season – the competition’s second – was played in South Africa, both times to avoid clashes with the country’s general elections. (Cricket.com.au)
The grand finale is slated for Sunday September 29, which is the actual birthday of the club.Speaking at a press briefing at the club to intimate journalists of its activities on Tuesday, Vice Chairman of Ikoyi Club 1938, Tafa Zibiri- Aliu, who also doubles as Chairman, Anniversary Sub Committee said the club is built on the foundation of global harmony through recreation.He said: “The theme of this year’s anniversary ‘’Building Family Values’’ is targeted at ensuring that apart from the club achieving global harmony through recreation, members of the club and families are encouraged to see Ikoyi Club 1938 as a veritable ground for bonding together.”“The dynamism being experienced in the club today is none other than the contributions of the past and present administrations who have continued to work tirelessly in seeing to the growth and development of the club,” Zibiri- Aliu said.Share this:FacebookRedditTwitterPrintPinterestEmailWhatsAppSkypeLinkedInTumblrPocketTelegram As part of activities to mark the 81st birthday anniversary of Ikoyi Club 1938, the club last Saturday kick-started the anniversary with a 7.5km charity walk.Tuesday was the Music Night, while Wednesday was Elders Day, a day specially made to celebrate elders who had contributed so much to the development and growth of Ikoyi Club 1938.On Thursday members of the club visited the old peoples home and was also the Anniversary Lecture Day. Anniversary Turn Up/ Pub Night took place on Friday, while today is Family Fun Day which is also designed for the entertainment of members wives and children.
Qantas Airways and American Airlines announced they have received regulatory approval to commence joint business between North America and Australia/New Zealand.Qantas Airways head of industry and corporate sales, Karen Tsolakis and American Airlines vice president Theo Panagiotoulias said the joint partnership will allow both airlines the ability to provide its customers with increased flight options and more connection opportunities within the U.S. and Australia New Zealand.“It will also provide access to a wider variety of fare levels,” the airlines said in a joint statement.The joint venture continues to grow with American Airlines code placed on Qantas flight between Dallas /Fort Worth and Sydney.Similarly, Qantas Airways has its code beyond Los Angeles, Dallas/Fort Worth and New York JFK on American’s services.In addition, the carriers frequent flyer benefits remains entirely reciprocal.“We are working to align our sales policies and procedures particularly for premium customers and where possible, integrate our customer support,” the airlines said in a joint statement.Ms Tsolakis and Mr Panagiotoulias also thanked the travel industry for supporting them and as they implement the improvements of the partnership it will provide further information. Source = e-Travel Blackboard: S.P
Source:https://www.brighamandwomens.org/about-bwh/newsroom/research-briefs-detail?id=3087 Jul 31 2018Two new studies published by investigators from Brigham and Women’s Hospital illustrate that not all forms of amyloid-beta (Aβ) protein – the protein thought to initiate Alzheimer’s disease – play an equally menacing role in the progress of the disease. Using a new way of preparing and extracting the protein as well as a new technique to search for promising drug candidates, researchers have highlighted the importance of testing and targeting different forms of Aβ. Their work may help advance the search for more precise and effective drugs to prevent or halt the progress of Alzheimer’s disease.”Many different efforts are currently underway to find treatments for Alzheimer’s disease, and anti-Aβ antibodies are currently the furthest advanced. But the question remains: what are the most important forms of Aβ to target? Our study points to some interesting answers,” said Dominic Walsh, PhD, a principal investigator in the Ann Romney Center.Related StoriesMachine learning can be a modern approach in cognitive brain health assessmentUAB scientists identify new target for drug intervention in Alzheimer’s diseaseNew route to quickly transport subcutaneously administered antibodies into lymph nodesAβ protein can take forms ranging from monomers – single molecules – to twisted tangles of plaques that can pollute the brain and are large enough that they can be seen with a traditional microscope. Walsh compares monomers to single Lego bricks, which can start sticking together to form complex structures of varying sizes. The two recently published studies investigate how to find new potential therapeutics that can target the structures most likely to cause harm.Most Alzheimer’s disease studies use synthetic Aβ to approximate what conditions in the brain of an Alzheimer’s patient might be like. A small number of researchers have used Aβ extracted from human brain, but the extraction process is crude. In a study published in Acta Neuropathologica in April, Walsh and colleagues developed a much gentler extraction protocol to prepare samples from subjects with Alzheimer’s disease. The team found that Aβ was far more abundant in traditional crude extracts, but that the bulk of the extracted Aβ was innocuous. In contrast, much less Aβ was obtained with the gentler protocol, but in this case most of the Aβ was toxic.In a second study published in Nature Communications in July, Walsh and colleagues developed a screening test to try to find potential drugs to target the toxic forms of Aβ. The new technique uses extracts of brain samples from Alzheimer’s disease patients and live-cell imaging of stem-cell derived brain cells to find promising therapeutics. The team reports on 1C22, an Aβ antibody that they found could protect against toxic forms of amyloid-beta more effectively than the most clinically advanced Alzheimer’s disease therapeutics currently in clinical trials.”We anticipate that this primary screening technique will be useful in the search to identify more potent anti-Aβ therapeutics in the future,” said Walsh.